Leverage Single-Cell Multi-Parametric Datasets to Advance Heme Oncology Pipelines
Time: 2:20 pm
day: Day Two Track A
Details:
- Leverage single-cell multi-modal analysis to get a more comprehensive view of multiple myeloma disease progression, therapy response and resistance, and therapy safety/efficacy
- Integrate SNVs, zygosity, CNVs, VDJ clonotype, and surface immunophenotype at the single-cell level, while measuring the transduction efficiency and vector copy number of potential CAR-T therapies
- Assess genome integrity through genome-wide CNV analysis at the single-cell level and leverage cohort-level analysis to guide therapeutic and clinical development
