Jorge DiMartino

Chief Medical Officer & Executive VP, Clinical & Translational Development Plexium Inc.

Seminars

Tuesday 23rd September 2025
Developing a Companion Diagnostic for a SMARCA2 Direct Degrader in Cancer
11:50 am
  • SMARCA4 mutations are a heterogeneous group of genomic abnormalities in cancer, some of which create a dependency on its paralog, SMARCA2
  • Prospective identification of patients who would benefit from treatment with a selective SMARCA2 degrader will require a comprehensive analysis of data from ongoing clinical studies and pre-clinical models
Jorge DiMartino