The Multifaceted Role of GEF-H1 in Cancer & Its Immune Activation by Plinabulin

  • Revisiting the role of the microtubule-associated RhoA activator GEF-H1 in cancer
  • GEF-H1 activation by plinabulin in DC maturation and anticancer immune responses
  • The potential of GEF-H1 based biomarker approach for plinabulin combined with chemotherapy/ radiation and a checkpoint inhibitor