Nancy Krunic, Ph.D
Seminars
Tuesday 6th October 2026
Panel Discussion: Strengthening Tumor‑Informed MRD Assays with Standardized Analytical Validation to Ensure Reliable Detection & Confident Clinical Interpretation
6:10 pm
- What factors define intended use for MRD at predefined post-surgery time points and how to align study designs to qualitative detection endpoints?
- How to design precision repeatability and reproducibility across instruments, operators and sites under clinical sample scarcity?
- How can assay accuracy be robustly established when orthogonal reference methods are less sensitive than the MRD assay?
Wednesday 7th October 2026
Neurofilament: The Journey of a General Marker of Axonal Damage to a Biomarker with Clinical Utility in Multiple Sclerosis & Future Utility in Multiple Indications
4:40 pm
- Overview of evidence generation for neurofilament light chain over the last 10 years
- Importance of robust diagnostic testing systems with established performance characteristics for neurofilament testing in clinical trials
- Drug-diagnostic co-development in MS and neurodegenerative disorders
