Mike Kagey
Vice President, Translational Medicine Leap Therapeutics
Seminars
Thursday 25th September 2025
Plasma DKK1 Levels are Associated with DKN-01 Clinical Activity in Colorectal Cancer
11:30 am
- Peripheral DKK1 is elevated in many cancers, often leading to worse clinical outcomes
- DKN-01 in combination with standard of care therapy has demonstrated compelling clinical data in CRC with enhanced activity in patients with elevated plasma DKK1
- CDx development of a plasma DKK1 ELISA assay is undergoing development to support the DKN-01 CRC clinical program
