Jason Baum

Jason Baum

Company: Leap Therapeutics

Job title: Vice President, Translational Medicine


Tumoral DKK1 as a Predictor of Outcomes and Response to DKN-01 3:50 pm

• DKK1 is overexpressed in many cancers, often leading to worse outcomes by promoting cancer cell proliferation, metastasis and angiogenesis • DKN-01 as a monotherapy and in combination has demonstrated compelling clinical data in multiple indications including gastroesophageal cancer, with enhanced responses seen in DKK1-high patients • DKK1 CDx development to support the clinical development…Read more

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