Ellie Corigliano

Ellie Corigliano

Company: GlaxoSmithKline

Job title: Head of CDx Cell & Gene Therapies Oncology


Panel Discussion: How to Know When a CDx & a Predictive Biomarker is Needed for a Drug 3:30 pm

Discussing criteria determining which drugs to progress for CDx selection to inform clinical strategy and investment plan Changing requirements to implement a diagnostic in the early phase clinical trial Vs what’s needed for later approval Engaging different arms of the business, to build trust for CDx development Pre-empting bottlenecks in Dx development to de-risk investmentRead more

day: Day One

Use of NY-ESO-1 TCR T-Cell Therapy in Patients with Mixed Round Cell Liposarcoma Whose Tumors are NYESO-1 Positive 1:30 pm

Letetresgene autoleucel (lete-cel; GSK3377794) is a T-cell receptor (TCR) T-cell therapy specific to the NY-ESO-1 peptide-displaying antigen, a highly immunogenic cancer/testis antigen expressed in myxoid round cell liposarcoma that promotes an anticancer immune response Early development of NY-ESO-1 immunohistochemistry detection suggests a companion diagnostic path forward for clinical developmentRead more

day: Track B - Day 1 PM

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