Panel Discussion: Strengthening Tumor‑Informed MRD Assays with Standardized Analytical Validation to Ensure Reliable Detection & Confident Clinical Interpretation
- What factors define intended use for MRD at predefined post-surgery time points and how to align study designs to qualitative detection endpoints?
- How to design precision repeatability and reproducibility across instruments, operators and sites under clinical sample scarcity?
- How can assay accuracy be robustly established when orthogonal reference methods are less sensitive than the MRD assay?